Pentobarbital will decrease the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of buspirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. When barbiturates like Nembutal are abused, they are not usually the primary drug of abuse. Like https://iwanttobookmark.com/story20427447/pentobarbital-vs-phenobarbital-una-panoramica