Epidural clonidine applied as an adjunct to local anesthetics has 3 different mechanisms of action. Initially, the stimulation of alpha-two-receptors while in the dorsal horn decreases suffering transmission. Secondly, clonidine can result in nearby vasoconstriction that boundaries vascular elimination of regional epidural anesthetics. Extreme Allergic Reactions. Clonidine could induce https://www.proleviate.com/post/the-new-pain-killer-conolidine