Telomere chromatin structure is pivotal for maintaining genome stability by regulating the binding of telomere-associated proteins and inhibiting the DNA damage response. In Saccharomyces cerevisiae. silent information regulator (Sir) proteins bind to terminal repeats and to subtelomeric X-elements. resulting in transcriptional silencing. https://www.chiggate.com/3m-speedglas-9002nc-welding-helmet-fashion/