At an oral dose of 2000 mg/kg/day in rats, maternal toxicity and deaths were being viewed with an increased incidence of early fetal resorption; spontaneous abortions transpired in cynomolgus monkeys on the maternally toxic oral dose of 2000 mg/kg/working day; there are no adequate and perfectly-controlled trials in pregnant Women https://williamh544sep7.tnpwiki.com/user