Ligases (or synthetases) - couple the breakdown of a pyrophosphate bond in a very nucleotide for the formation of recent chemical bonds The speculation that enzyme specificity results from your complementary nature on the substrate and its Lively site was very first proposed via the German chemist Emil Fischer in https://louiscjoty.wikidirective.com/6803005/the_fact_about_gewonnen_that_no_one_is_suggesting