Does Creatine Lead to Constipation? Creatine is a well-liked supplement used by athletes and bodybuilders to increase muscle mass. Though it's been verified to generally be effective in assisting folks build strength, there are several probable Unintended effects which have been linked with creatine use, such as constipation. https://tornadosocial.com/story1517812/does-creatine-cause-constipation